Genome of a Pompeii victim decoded for the first time

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Researchers from the University of Salento in southern Italy and the University of Copenhagen have for the first time managed to decipher the entire genome of a resident of the ancient city of Pompeii who died when Mount Vesuvius erupted in AD 79. The man’s genome sequencing shows that he may have contracted tuberculosis (TB) and was related to humans in Sardinia.

Specifically, the team of scientists, led by Gabriele Scorrano, looked at the genetic material of two deceased people from the so-called “Casa del fabbro” (English: “House of the craftsman”). It used parts of the petrous bone, a bone in the skull. They extracted DNA from the remains, which belonged to a man between the ages of 35 and 40 and a woman in her 50s.

The man’s genome has been fully sequenced, while that of the woman has significant gaps. Comparing the results with genetic information from 1030 ancient West Eurasian individuals suggests that the Pompeians had many similarities with the inhabitants of central Italy and other peoples who inhabited the center of the Italian peninsula during the Roman Imperial era.

Relatives in Sardinia
At the same time, the scientists were also able to identify typical gene clusters for communities living on the island of Sardinia. These results indicate a possible genetic exchange in the period before Vesuvius erupted, the experts reported.

Indications of Tuberculosis Disease
The researchers also found DNA sequences from mycobacteria, which are widely believed to cause tuberculosis or leprosy. Lesions in one of the vertebrae also suggest that the man contracted tuberculosis before he died. This work provides valuable information about the genetics and life of the people who lived in Pompeii, according to the experts.

The ancient city of Pompeii is located at the foot of the volcano Vesuvius. During eruptions in AD 79, ash, mud and lava buried the settlements and partially preserved the city and its inhabitants. Pompeii was not rediscovered until the 18th century. The excavation site is one of the most popular sights in Italy and always uncovers sensational finds.

Source: Krone

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