Vecht against Malaria – A random find makes people a gelval

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A random find can cause a revolution in the fight against one of the most fatal infectious diseases in the world. Scientists have discovered that an already approved medication makes human blood a fatal danger to the depression of Malaria.

An already approved medication for a rare metabolic disease makes human blood toxic to pieces of malaria. This has found an international research team with Swiss participation.

Also helps against other resistant gels
The active ingredient called Nitisinon inhibits an enzyme that the mosquitoes need to digestion, such as the US researchers, the United Kingdom and Switzerland have shown in a study published in “Science Translational Medicine” on Wednesday.

Human blood that contained the active ingredient quickly killed both young and old malaria pieces. It also worked against mosquitoes that were resistant to insecticides. It was tested in the MUG Anopheles Gambiae, the most important airline of the malaria in African countries.

Treatment still very expensive
However, the active ingredient nitisinon is expensive, as the researchers allow in the research. Nitisinone treatment therefore costs up to $ 380,000 a year. “However, the reuse of nitisinon for mosquito fighting can help to lower the costs of the drug and increase its availability for rare diseases,” the researchers write in the study.

The research team then plans further studies to find out which doses nitisinon are most effective against mosquitoes in practice. In Switzerland, the active ingredient for the treatment of rare metabolic disease Tyrosinemia type 1 has been approved.

In the study, Didier Leroy of the public-private partnership “Medicines for Malaria Venture (MMV)” were involved in the study from Switzerland.

Source: Krone

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