To date, many people suffer from the long-term consequences of a COVID 19 infection. The disease is now better understood. A study by the Meduni Vienna has now shown that patients have changed inflammatory makers and a disturbed intestinal barrier.
This could help to develop post-viral fatigue, announced, announced by immunologist Eva Untersmayr-Elsenhuber. The scientists investigated the course of COVID-19 infections as well as gastrointestinal complaints before, during and after the infection. The result: anyone who had gastrointestinal complaints before a COVID 19 disease has a higher risk to develop PCS-Fatigue.
At the same time, striking changes were found in certain biomarkers that indicate a changed immuneactivation and a reduced bowel barrier. There were elevated IL-6 mirrors that are considered a marker for systemic inflammatory reactions. “Our results indicate that a SARS-COV-2 infection can have long-term effects on the immune system and the intestinal health that contribute to the rise of PCS,” said Ungentmyr-Esenhuber.
“It is especially exciting that our participants in the study were usually young and healthy before the infection. Even the COVID disease usually only mild or even asymptomatic. A difference was the more often reported gastrointestinal complaints in the group, which developed post-viral fatigue,” added author Johanna Rohrhofer. According to the research team, monitoring of gastrointestinal symptoms and biomarkers can help identify risk patients at an early stage.
Post-conscious syndrome or PCs are the long-term damage to the infectious disease COVID-19. This means symptoms that occur again or for the first time twelve weeks after the start of the disease and cannot be explained by other causes. Moreover, they must last at least two months. Fatigue is a medical concept with which a pathological weakness is called.
Source: Krone
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