Balds send life -threatening pathogens for people without developing it themselves. An Austrian-German research team has now investigated why this is the case. Accordingly, viruses are prevented in the lung mucosa.
This has to do with his “considerably stronger antiviral basic defense” compared to people, according to the specialized magazine “Nature Immunology”. The team around Max Kellner of the Institute for Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences (ÖAW) in Vienna knitted organoids from lung and small intestinal cells and infected them in a laboratory with a high authority with Marburg viruses. “The Nile Flight Dog is considered a natural host of the very pathogenic Marburg virus, which can cause heavy hemorrhagic fever in people, which is fatal in 30 to 90 percent of the cases,” the scientists said.
They discovered that tons of messenger substances were released in the organoid. This is a central part of congenital immune weather and would fight viral infections by activating hundreds of antiviral genes, Kellner said. “Probably these bats enable to control the virus increase of the mucous membrane early, while human cells less effectively recognizes the Marburg virus at the start of the infection, which means that it can spread freely in the body.”
Protection will continue for a long time
Breathing jobs are therefore able to prevent uncontrolled virus improvements. The messenger substances not only caused a strong immune response in the escape dogs, they even strengthened themselves in their work. This ensures a long -term protective effect against viruses, according to the researchers.
Source: Krone

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